1.Tooth characteristics of ligation tissue closure clips

The design of the teeth of tissue closure clips is critical to their function. The teeth are usually characterized by non-slip teeth, snap locks, and bowed legs. The anti-slip teeth are designed to increase the contact area between the teeth and the blood vessels or tissue bundles during closure, which makes the closure more tight and less likely to slip off. This design not only improves the clamping force and closure reliability of the closure clip, but also prevents possible lateral slippage and popping open of the clamped tissue under the action of elastic recovery force. The buckle lock ensures that the clip is securely locked in place during the clamping process to prevent accidental release. The design of the bow-shaped nail leg makes the ligation more secure, while the design of the elastic hinge makes the ligature lock close and open with a certain degree of expansion and contraction space, so that it will not be loosened or dislodged due to the subsiding of the edema of the clamped blood vessels or tissues.

2. Differences in closure

Different types of tissue closure clips have significant differences in closure. Titanium metal clips, due to their hard material, provide strong holding power during closure, but may also loosen as tissue edema subsides. Absorbable clips, such as those made of polylactic acid or polynate, are biocompatible but have relatively weak mechanical properties, and the physician may not be able to hear a crisp snap sound during clamping closure, increasing operational uncertainty. On the other hand, closure clips made of polymer materials, such as those made of the inert polymer material polyoxymethylene (POM), not only have excellent biocompatibility and safety, but also have a clear sense of touch when they are clamped shut, which ensures that the ligation process is fast, safe and efficient.

3. Advantages of the tooth morphology of different closure clips

The tooth morphology of different closure clips has its own advantages. Titanium metal clips usually have sharp teeth, which provide high penetration and holding power, but may be too sharp and cause damage to surrounding tissues. Absorbable clips have teeth that are designed to be relatively soft to minimize tissue damage, but this may also result in relatively weak gripping power. The teeth of polymer closure clips combine the advantages of both, providing adequate holding power while minimizing tissue damage. In addition, the design of the teeth of polymer material closure clips also takes into account the need for anti-slip and anti-dislodgement, which improves the reliability and safety of the clip closure by increasing the contact area and anti-slip teeth.

4. Design considerations and starting point

In the process of organizing the design of the closure clip, we have mainly considered the following aspects:

Safety: Ensure that the closure clip will not cause damage to the surrounding tissues during use, and at the same time can firmly hold the target tissues to prevent slipping or falling off.

Biocompatibility: Select materials with excellent biocompatibility to minimize rejection and inflammatory reactions and ensure patient safety and comfort.

Functionality: According to the surgical needs, different sizes and forms of closure clips are designed to meet the needs of different parts and different tissues for clamping.

Economy: under the premise of ensuring quality and safety, reduce the production cost as much as possible to alleviate the economic burden of patients.

In summary, the design of Donho tissue closure clips is a complex and delicate process that requires comprehensive consideration of many aspects. Through continuous research and innovation, we are committed to providing patients with safer, more effective and economical medical device solutions.